February 17th, 2012 Chitin in cancer clinical medicine application
liaoning province tumor hospital (shenyang 110042) ZhaoChaoChen
21 century two killer a is AIDS another is the cancer. In our country’s cancer has is harm common disease of the health of urban and rural residents, accounting for the city’s cause of death. The second cause of death. Cancer causes complex, now think is a comprehensive effect of pathogenic factors, namely and external environment of carcinogenic chemicals, ionizing radiation, virus chronic infection related, at the same time and their own genetic, cancer and induced cancer gene, immune function is closely related to the level.
reported in the literature chitin has to restrain human body cell aging, slow decay activation cell function, regulate intensify immune monitoring capacity and improve endocrine coordination viscera function, row poison detoxification improve human self-healing force and other functions. So of cancer prevention and treatment of each phase with chitin has close livre DE ma mere relationship.
an, chitin and cancer
the human body is composed of 6 quadrillion cells composition and like all life has a certain life, aging itself every cell near 107-9 cell mutations (distortion) there will be ten thousand cancer cells to produce, the immune function of normal people rely on its own immune system is mainly cellular immune and humoral immune, the extensive damage against cells-NK cells, activate the generation of interleukin immune lymphocytes-LAK cells, phagocytic cells and of macrophage phagocytosis to strictly control the total number of cancer cells in 104 the following, the human body from the cancer problem. Old or sick because of low immune function suppressor ability there must be limited potential danger, high-risk groups to take necessary health measures to keep or regain enough to the immunity of the disease is very important.
ecological balance by people in the diet can mental health facilities getting enough chitin record to complete the activation cell adjusting immunity etc. Function. The modern life of natural food chain is destroyed with simple test to meet demand must take every day, 0.3-0.5 g can improve human body environment of the pH (pH) because only in weak alkali T lymphocytes and beta lymphocytes more active, and at the same time also can increase immune cell activity the quantity and quality of play the cancer-fighting properties.
2, ZhiDui shell the therapeutic effect of cancer
cancer cells are fleeing the body’s immune surveillance system, according to their own ratio of cell populations are infinite value, the body number 106-9 in cancer cells, the modern medical testing means is insufficient to discover in time, host and abnormal symptoms without signs much less to hospital for treatment. This one phase in medicine called cancer and clinical period. When the body of the cancer cells of a total of 109 total volume is about 1.0 CM3, use some specific tests, X-ray, CT and MRI imaging, endoscopy, etc can be found early, just come on in general a minority. Literature report antitumor biological agents interleukin Ⅱ, interferon, anticancer RNA, XiongXianTai, transfer factor, necrosis factor has certain anti-cancer effect by increasing recognition and kill cancer cells slow cancer cells cancer cells is the effective way of proliferation rate, but too much and not use time cancer biological agents can cause the body’s immune close condition, once out of service, the cancer cells will quickly and overall treatment against proliferation.
cancer drugs commonly used), agents, anti-cancer antibiotics, resistance to metabolic drugs and miscellaneous class, most of these toxic substances in kill cancer cells at the normal cell damage is very big also, so that by various restrictions. The European and American countries is working on a new kind of cancer drugs-cancer cells capillary endothelial cells generate drugs mainly chitin, heparin and peptide, its mechanism is the cancer of the blood capillary blood capillary endothelial cells, and whether a capillary endothelial cells two kinds, only has the capillary endothelial cells can extend the capillary extension, cancer cells along the capillary around to infiltrate tumor size increase. Chitin antidepressants capillary endothelial cells generate drugs, inhibit the growth of blood capillary, will the cancer control in local. Chitin in the adjustment of the ph and strengthen the immune improve human body to kill cancer cells in the cancer early and realize the anti-cancer, if can grasp opportunity timely applying the anti-cancer effects with simple test has special significance.
three, college application in treatment of chitin has a good synergy
surgical resection, radiotherapy and anti-cancer drugs is the treatment of cancer three conventional methods, in recent years have been developed into the above three methods and other various treatment method combined application that is comprehensive treatment, and carry out the comprehensive treatment effect is improved greatly. Clinical have observed with timely chitin has a certain value. Radical surgery should be naked eye saw no cancer tissue residues, palliative operation should also removed more than 80% of cancer tissue, who remain in 109 the total number of cancer cells, chitin used alone or better anti-cancer effect, its mechanism as aforesaid. Surgery patients in the process of blood loss of salt and water liquid metabolic disorder, infection of incision delay healing, local inflammatory and the inflammatory oozy, pain, whole body condition decline were recovering, make the perioperative treatment later extended, interference. This time should take to improve from the chitin force shorten perioperative, can create favorable conditions for other treatment.
another expanded localized treatments-radiotherapy is developed in the last decades of the professional, is a damaged the treatment will have the strict indications, do not abuse. When the in vitro illuminate strong ionizing radiation by the body into treatment area, through the radiation physicians and electronic computer treatment planning systems make use more wild much direction illuminate the cancer accept lethal dose, near the cancer the normal tissue accept the lowest dose, plus the cancerous tissue and normal tissue repair the time on that cancer cells repair slow and normal tissue cells repair so as to realize the quick treatment function. Ionizing radiation in the body and organization of cancer cells have direct and indirect two kinds of action, direct role is to make radiation caused by cells chromosome chain or single league double rift to death and the fatal injury. Indirect effect is the main material component cells of produced water ionization oxide hydroxyl radicals. Radiation in the short time 10 to 5 seconds of free radicals, produce the large amount of poisonous exhausted body radiation super oxide dismutase defense system the interference and damage which the cell active substances mitochondria, golgi apparatus, RNA and deoxyribose nuclear, etc, the human body corresponding produce radioactive inflammation, local acid product accumulation severe pain, bone marrow, suppression, digestive breathing function obstacle, human body becomes failure cause radiation interrupt, radiation can’t on schedule make curative effect reduced.
for many years have been seeking to solve radiotherapy experts to the side effects of radiation, use of high oxygen and low oxygen radiation therapy, use radiotherapy sensitization agent and protectants are not effective. The clinical observation radiation also take chitin satisfied with the results, chitin the polysaccharide positively charged cationic group, due to the human body is an important material constitute the basic unit of hyaluronic acid, and cells have excellent compatibility with strong absorption dissolved after the adsorption capacity, capture and bond with free radicals to eliminate or reduce its toxicity, ensure the normal radiotherapy.
due to the increase of the proportion in middle-late cancer application cases of cancer drugs are becoming more and more most of the cancer drugs is cellular toxic substances, kill the cancer cells have positive effects of cancer control, also have a killer normal cells, the damage to the side effects, the patient often in the application of nausea vomiting, bone marrow, inhibit the whole blood or granulocytopenia, drug sex liver and kidney inflammation. Practice proves to plenty of chitin and anti-cancer drugs degradation products form complex or complex, the liver, kidney, intestinal cavities, chitin in combination chemotherapy can increase the curative effect, slowing down side effects, show a good synergy effect.
with antitumor clinical medicine development, and comprehensive treatment increasingly important, surgery, radiotherapy and chemotherapy combined with or by increase, curative effect is improved greatly. Treatment requires patients whole body condition is higher, the whole body support and auxiliary medicine is more important. Reasonable auxiliary medicine should be able to reduce the adverse reaction of chemotherapy put, improve the body immunity, the characteristics of shell that is an ideal health products, has the role of evaluation.
four, chitin to prevent cancer metastasis in the application of
cancer for the harm to human body is mainly local the cancer and viscera transfer out of control. The cancer cells through blood and lymph circulation, migrated to a distant tissues and organs, first form tumor emboli again development into nests, and finally form the cancer the transfer of complete carcinoma, the whole process of the key is the movement of cancer cells and adhesion. The cancer cells natural lost or mechanical extrusion stimulate le
